View source for CBD Clinical Trial Results On Seizure Frequency In Dogs encouraging

<br>McGrath, a neurologist at Colorado State University's James L. Voss Veterinary Teaching Hospital, led a small study with 16 pet dogs to assess the short-term effect of CBD on seizure frequency. Based on her research, McGrath found that 89 percent of dogs who received CBD in the clinical trial had a reduction in the frequency of seizures. Nine dogs were treated with CBD, while seven in a control group were treated with a placebo. The research took place from 2016 to 2017, and results are published in the June 1 issue of the Journal of the American Veterinary Medical Association. Idiopathic epilepsy, which occurs with no known cause, affects up to 5.7% of the pet dog population worldwide, making it the most common canine neurologic condition. Dogs enrolled in the clinical trial were randomly assigned to the treatment or placebo group. Those in the treatment group received CBD oil for 12 weeks. All of the dogs were required to stay on standard anticonvulsant drugs, including phenobarbital and potassium bromide. The dogs' owners and CSU medical staff did not know if the animal received CBD or a placebo until the study was complete. The CBD product used in the study was derived from a hemp plant, which has 0.3 percent or less of the psychoactive component of cannabis, THC. The compound is not considered marijuana and can be used for research purposes based on the 2014 United States Department of Agriculture Farm Bill.<br><br><br><br>CBD (cannabidiol) and THC (tetrahydrocannabinol) are the two major compounds found in the cannabis plant. Each has unique properties, potential [http://154.209.4.10:3001/celinafinnis7/global-health-farms2021/wiki/Delta-eight+THC+Products+are+Illegal+in+Texas%252C+Updated+Health+Department+website+Says Buy Global Health Farms CBD] benefits, and side effects. The following article covers CBD and THC, their effects, their legal status, and their safety considerations. [http://109.74.197.189/emilyscholl201/6016global-health-farms-hemp-gummies/wiki/CBD+Skincare+Guide+-+Associated+CBD.- CBD Gummies by Global Health Farms] and THC are known as cannabinoids. They have very similar chemical structures and activate the same receptors within the body’s endocannabinoid system. Despite their similarity in structure, CBD and THC exert entirely different effects. The most significant difference between these two compounds is that THC is psychoactive. This means it can affect how the brain works. [http://dig.ccmixter.org/search?searchp=THC%20activates THC activates] the body’s "reward" pathways to produce the "high" that’s associated with marijuana use. It does this by activating a cannabinoid receptor called CB1. When THC activates this type of receptor, things like movement, body temperature, and brain function are affected. In contrast, CBD is not considered psychoactive. It does not cause euphoria or a "high," even at large doses.<br><br><br><br>Much of the research on CBD and THC is preclinical, meaning it’s been studied in animal models. Large-scale human trials are necessary to determine if CBD or THC can help treat most of these conditions. Though it does act on cannabinoid receptors, CBD mainly affects other receptors, including serotonin receptors. It may help counteract some of the negative effects of THC, including serious side effects like psychosis. CBD has many purported therapeutic properties. Pain. Overall, there isn’t enough evidence that CBD by itself helps with pain. Some research has shown that high doses can improve neuropathy (nerve pain), though more data is necessary. Anxiety. So far, the results are mixed. Some studies show that CBD can improve symptoms of social anxiety disorder and post-traumatic stress disorder (PTSD), while others show no effect. Seizures. Epidiolex, a purified CBD oil, is approved by the Food and Drug Administration (FDA) for some hard-to-treat types of childhood epilepsy.<br><br><br><br>Brain protection. Animal studies have shown that CBD may have benefits for those who have Alzheimer’s disease or Parkinson’s disease, but human clinical trials are necessary to verify these effects. Effects on animals may or may not translate into benefits for humans. THC is the psychoactive ingredient from the marijuana plant. The possession and use of marijuana and THC-containing products are not legal in all U.S. THC is effective for increasing appetite and for nausea and vomiting related to cancer chemotherapy. Pain. Prescription THC products have been shown to improve neuropathy and quality of life. Spasticity (muscle tightness). Sativex (nabiximols), a mouth spray that combines THC and CBD, is approved for  GHF CBD Gummies spasticity in Europe. PTSD. A very small trial found that Cesamet reduced nightmares in 10 military personnel with PTSD. Irritable bowel syndrome (IBS). Smoking THC was found to improve symptoms of IBS, but benefits may be only short-lived. People who used THC long-term were more likely to ultimately require surgery for IBS.<br><br><br><br>Notably, most of the research into THC’s effects has used standardized THC prescription medications. Other THC-containing products available at dispensaries may or may not be beneficial for any of these conditions. More research is undoubtedly necessary. Understanding how CBD and THC are regulated in the United States is a bit tricky. Basically, it comes down to the source of the product, whether it comes from the marijuana plant or hemp plant. In 2018, the U.S. CBD that contains less than 0.3% THC. Plants that contain this low concentration of THC are known as hemp. Historically, hemp has been used to make things like fiber and paper. Notably, marijuana (which comes from a cannabis plant with more than 0.3% THC) remains a Schedule 1 controlled substance. This means that the FDA considers it to have a high risk of abuse and no accepted medical use. Accordingly, CBD and THC that come from a marijuana plant are also Schedule 1 controlled substances.<br>